Picolinic acid → HCID 4877715, compound

HRID 1583990Notes

Reaction equation

HRID 1583990 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[C:7]([OH:9])=O.C(N1C=CN=C1)(N1C=CN=C1)=O.[N:22]1([CH2:27][CH2:28][CH2:29][NH2:30])[CH:26]=[CH:25][N:24]=[CH:23]1>O1CCCC1>[N:22]1([CH2:27][CH2:28][CH2:29][NH:30][C:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)=[O:9])[CH:26]=[CH:25][N:24]=[CH:23]1

Participants

5

Reactant 3

HCID 1018Picolinic acidHCID 682631,1'-CarbonyldiimidazoleHCID 787361H-Imidazole-1-propanamine

Product 1

HCID 4877715HCID 4877715, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Following the general procedure of Example 14 and reacting the appropriate pyridinecarboxylic acid derivative with 1,1'-carbonyldiimidazole and 1H-imidazol-1-propanamine in tetrahydrofuran, the compounds of Examples 15-17 found in Table IV were prepared.

Workup

  1. customwere prepared

Sources & evidence

ORD record
ord-e2adcfacdcef488083aae54f19e5d53c
Source dataset
uspto-grants-1985_11
Patent number
US04555519

Reaction notes

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