反应详情

A solution of 3.6 g of 2-hydroxyethyl hydrazine in 5 ml of methanol and 20 ml of THF was added over 1.5 hours to a mixture of 6.09 g of 1-chloro-7-methoxy-4-nitro-9(10H)-acridinone in 75 ml of methanol and 55 ml of THF, and the resulting suspension was stirred 20 hours at room temperature. The precipitate was collected and recrystallized from DMSO-methanol, providing 9-methoxypyrazolo[3,4,5-kl]acridine-2(6H)-ethanol, mp 275°-276° C.

1. customThe precipitate was collected
2. customrecrystallized from DMSO-methanol