Hydrochloric Acid → HCID 178518939, compound

HRID 1585982Notes

Reaction equation

HRID 1585982 reaction equation
O.[NH2:2][NH2:3].Cl.[C:5]1(=O)[O:10][C:8](=[O:9])[C:7]2[CH2:11][CH2:12][CH2:13][CH2:14][C:6]1=2>O>[OH:9][C:8]1[C:7]2[CH2:11][CH2:12][CH2:13][CH2:14][C:6]=2[C:5]([OH:10])=[N:3][N:2]=1

Participants

5

Reactant 3

HCID 313Hydrochloric AcidHCID 124753,4,5,6-Tetrahydrophthalic anhydrideHCID 24654Hydrazine hydrate (1:1)

Product 1

HCID 178518939HCID 178518939, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

25 ml of purified water was added to 1.7 ml(0.035 mol) of hydrazine monohydrate and then 7 ml(0.07 mol) of conc. hydrochloric acid was added dropwise thereto. Then, the reaction solution was warmed to boil. When the reaction mixture begins to reflux, 5.33 g(0.035 mol) of 3,4,5,6-tetrahydrophthalic acid anhydride was added thereto. The reaction solution was continuously refluxed for 3 hours and then cooled. Then, the reaction solution was treated according to the same manner as Preparation 1 to obtain the title compound as an white needle crystal.

Workup

  1. temperatureThen, the reaction solution was warmed to boil
  2. temperatureto reflux
  3. temperatureThe reaction solution was continuously refluxed for 3 hours
  4. temperaturecooled
  5. additionThen, the reaction solution was treated
  6. customaccording to the same manner as Preparation 1

Sources & evidence

ORD record
ord-c35edf2f99b141389c6e38a869acbacb
Source dataset
uspto-grants-1999_08
Patent number
US05942511

Reaction notes

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