Benzyl Bromide → HCID 86746955, compound

HRID 1587752Notes

Reaction equation

HRID 1587752 reaction equation
[C:1](=[N:10][OH:11])([C:4]1[CH:5]=[N:6][CH:7]=[CH:8][CH:9]=1)[CH2:2][CH3:3].[CH2:12]([Br:19])[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>C(OCC)(=O)C>[Br-:19].[CH2:12]([N:6]1[CH:7]=[CH:8][CH:9]=[C:4]([C:1](=[N:10][OH:11])[CH2:2][CH3:3])[CH2:5]1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 85840682HCID 85840682, compound

Product 1

HCID 86746955HCID 86746955, compound

Reagents, catalysts & solvents 1

HCID 8857Ethyl AcetateSolvent

Procedure

A mixture of 17.8 g of 3-propionyl pyridine oxime [(U.S. Pat. No. 3,004,979 (1961)] and 18 cm3 of benzyl bromide is maintained at reflux for 7 hours 30 minutes in 250 cm3 of ethyl acetate. After cooling and separating, 36.5 g of the expected product is obtained. m.p. 178°-180° C., recrystallized from an ethanol-ether mixture.

Workup

  1. temperatureAfter cooling
  2. customseparating

Sources & evidence

ORD record
ord-cfcd2ef009f548608c7f8261b5b2a4df
Source dataset
uspto-grants-1993_06
Patent number
US05219873

Reaction notes

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