Phenethylamine → HCID 19365555, compound

HRID 1600061Notes

Reaction equation

HRID 1600061 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[S:31][C:12]3[N:13]([CH2:23][C:24]4[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=4[F:30])[CH:14]=[C:15]([C:18]4[O:22][CH:21]=[N:20][CH:19]=4)[C:16](=[O:17])[C:11]=3[C:10]=2[CH2:32]Br)=[CH:5][CH:4]=1.C([N:36]([CH:40]([CH3:42])C)[CH:37](C)C)C.[CH2:43]([CH2:50]N)[C:44]1C=CC=[CH:46][CH:45]=1>CN(C)C=O>[CH2:40]([N:36]([CH2:32][C:10]1[C:11]2[C:16](=[O:17])[C:15]([C:18]3[O:22][CH:21]=[N:20][CH:19]=3)=[CH:14][N:13]([CH2:23][C:24]3[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=3[F:30])[C:12]=2[S:31][C:9]=1[C:6]1[CH:7]=[CH:8][C:3]([O:2][CH3:1])=[CH:4][CH:5]=1)[CH3:37])[C:42]1[CH:46]=[CH:45][CH:44]=[CH:43][CH:50]=1

Participants

5

Reactant 3

HCID 1001PhenethylamineHCID 81531DiisopropylethylamineHCID 19365560HCID 19365560, compound

Product 1

HCID 19365555HCID 19365555, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To a solution of the compound (0.07 g, 0.16 mmol) obtained in Example 2 in dimethylformamide (20 ml) are added under ice-cooling ethyldiisopropylamine (0.0243 g, 0.19 mmol) and N-benzylmethylamine (24.2 μl, 0.19 mmol).

Sources & evidence

ORD record
ord-eca0eaaf44904bcab96e2d09b4a5ad11
Source dataset
uspto-grants-1998_04
Patent number
US05744479

Reaction notes

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