Dimethyl Sulfoxide → HCID 13170313, compound

HRID 1602453Notes

Reaction equation

HRID 1602453 reaction equation
[CH3:1][C:2]1[O:3][C:4]2[C:5](=[C:7]([CH2:11][OH:12])[CH:8]=[CH:9][CH:10]=2)[CH:6]=1.CS(C)=O.C(Cl)(=O)C(Cl)=O>C(N(CC)CC)C>[CH3:1][C:2]1[O:3][C:4]2[C:5](=[C:7]([CH:11]=[O:12])[CH:8]=[CH:9][CH:10]=2)[CH:6]=1

Participants

5

Reactant 3

HCID 679Dimethyl SulfoxideHCID 65578Oxalyl chlorideHCID 18787473HCID 18787473, compound

Product 1

HCID 13170313HCID 13170313, compoundYield 93.4%

Reagents, catalysts & solvents 1

HCID 8471TriethylamineSolvent

Procedure

2-Methyl-benzofuran-4-methanol (3.34 g, 21 mmol) was oxidized using DMSO, oxalyl chloride, and triethyl amine similar to the above procedures to give the product as a clear oil (3.14 g, 93%).

Sources & evidence

ORD record
ord-f9e53cc3add744f483ee9c71a5a728a9
Source dataset
uspto-grants-1999_11
Patent number
US05981571

Reaction notes

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