反应详情

Alternatively, the solution of trimethyl-4-phosphonocrotonate in THF is deprotonated at -78° C. with a solution of lithium diisopropylamide (LDA), obtained from diisopropylamine and n-butyllithium, in THF, and the obtained anion reacted at -78° C. with a solution of an aldehyde IX in THF.