Potassium Cyanide → HCID 21540428, compound

HRID 1604896Notes

Reaction equation

[N:1]1[CH:6]=[CH:5][CH:4]=[CH:3][C:2]=1[CH:7]=O.[CH3:9][N:10]1[CH2:15][CH2:14][NH:13][CH2:12][CH2:11]1.[C-:16]#[N:17].[K+]>>[CH3:9][N:10]1[CH2:15][CH2:14][N:13]([CH:7]([C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][N:1]=2)[C:16]#[N:17])[CH2:12][CH2:11]1

Participants

Reactant 3

HCID 9032Potassium Cyanide

HCID 142732-Pyridinecarboxaldehyde

HCID 531671-Methylpiperazine

Product 1

HCID 21540428HCID 21540428, compound

Procedure

By the procedure of Example 23, 2-pyridinecarboxaldehyde is reacted with N-methylpiperazine and potassium cyanide to give 2-(4-methylpiperazino)-2-(2-pyridyl)acetonitrile.

Sources & evidence

ORD record: ord-944b737281a4411d8862110cb114f9c3
Source dataset: uspto-grants-1976_04
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US03948892

Reaction notes

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