Potassium Carbonate → HCID 14985850, compound

HRID 1613299Notes

Reaction equation

HRID 1613299 reaction equation
[C:1]([NH:4][CH2:5][CH2:6][N:7]1[C:11]([CH3:12])=[CH:10][CH:9]=[C:8]1[CH2:13][NH:14][C:15](=[O:17])[CH3:16])(=[O:3])[CH3:2].[Cl-].ClC=[N+](C)C.[C:24](=O)([O-])[O-:25].[K+].[K+]>ClCCCl>[C:1]([NH:4][CH2:5][CH2:6][N:7]1[C:11]([CH3:12])=[C:10]([CH:24]=[O:25])[CH:9]=[C:8]1[CH2:13][NH:14][C:15](=[O:17])[CH3:16])(=[O:3])[CH3:2]

Participants

5

Reactant 3

HCID 11430Potassium CarbonateHCID 77311Chloro-N,N-dimethylformiminium chlorideHCID 14985849HCID 14985849, compound

Product 1

HCID 14985850HCID 14985850, compound

Reagents, catalysts & solvents 1

HCID 111,2-DichloroethaneSolvent2×

Procedure

4.9 g of N-((1-(2-acetylaminoethyl)-5-methyl-1H-pyrrol-2-yl)methyl)acetamide in 70 ml of 1,2-dichloroethane are added dropwise to 3.0 g (21 mmol) of chloromethylenedimethylammonium chloride in 30 ml of 1,2-dichloroethane at 10° C. The mixture is subsequently stirred for 90 min, hydrolysed using potassium carbonate solution and worked up as described in Example 1.

Sources & evidence

ORD record
ord-ca1d7539e3f84f108a9749674f0f0858
Source dataset
uspto-grants-1993_03
Patent number
US05192795

Reaction notes

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