Hydrochloric Acid → 4,5-Bis(4-methoxyphenyl)-2-(2,4-difluorophenylthio)imidazole

HRID 162027Notes

Reaction equation

HRID 162027 reaction equation
[CH3:15][O:16][c:17]1[cH:18][cH:19][c:20](-[c:23]2[n:24][c:25]([SH:36])[nH:26][c:27]2-[c:28]2[cH:29][cH:30][c:31]([O:34][CH3:35])[cH:32][cH:33]2)[cH:21][cH:22]1.[CH3:39][N:40]([CH3:41])[CH:42]=[O:43].[ClH:14].[Cu:44].[F:1][c:2]1[c:3]([NH2:4])[cH:5][cH:6][c:7]([F:9])[cH:8]1.[N:10]([O-:11])=[O:12].[Na+:13].[Na+:38].[OH-:37]>>[F:1][c:2]1[c:3]([S:36][c:25]2[nH:24][c:23](-[c:20]3[cH:19][cH:18][c:17]([O:16][CH3:15])[cH:22][cH:21]3)[c:27](-[c:28]3[cH:29][cH:30][c:31]([O:34][CH3:35])[cH:32][cH:33]3)[n:26]2)[cH:5][cH:6][c:7]([F:9])[cH:8]1

Participants

9

Reactant 8

HCID 313Hydrochloric AcidHCID 923Sodium ion2×HCID 946NitriteHCID 961HydroxideHCID 6228DimethylformamideHCID 97092,4-DifluoroanilineHCID 23978CopperHCID 178489021HCID 178489021, compound

Product 1

HCID 128323094,5-Bis(4-methoxyphenyl)-2-(2,4-difluorophenylthio)imidazole

Sources & evidence

ORD record
ord-65c21d44978841a5a2f98836c1e5e2ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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