Sodium Carbonate → HCID 16752340, compound

HRID 1628364Notes

Reaction equation

HRID 1628364 reaction equation
Br[C:2]1[CH:3]=[C:4]([CH:7]=[C:8](Br)[CH:9]=1)[CH:5]=O.[C:11]1(B(O)O)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.[C:20](=[O:23])([O-])[O-].[Na+].[Na+]>C1COCC1>[C:11]1([C:8]2[CH:9]=[C:2]([CH:20]=[O:23])[CH:3]=[C:4]([C:5]3[CH:4]=[CH:3][CH:2]=[CH:9][CH:8]=3)[CH:7]=2)[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

5

Reactant 3

HCID 10340Sodium CarbonateHCID 66827Phenylboronic AcidHCID 6220773,5-Dibromobenzaldehyde

Product 1

HCID 16752340HCID 16752340, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

21.38 g (0.081 mol) of 3,5-dibromobenzaldehyde, 16.82 g (0.162 mol) of phenylboronic acid and 1.04 g (0.90 mmol) of tetrakispalladium are initially introduced. 500 ml of 1 M sodium carbonate solution and 300 ml of THF are added, and the reaction is brought to reaction under reflux for 24 h.

Workup

  1. customthe reaction is brought to reaction
  2. temperatureunder reflux for 24 h.

Sources & evidence

ORD record
ord-46a56b646544431db5632c79a141259c
Source dataset
uspto-grants-2014_07
Patent number
US08786181B2

Reaction notes

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