反应详情

A solution of 2-methoxy-4-(3-methyl-pyrazol-1-yl)-benzoic acid methyl ester (0.5 g) from Example 105 in tetrahydrofuran (2.5 ml) was treated with 1 N lithium hydroxide (2.13 ml) at room temperature. After 14 hours the solvent was removed in vacuo and the title compound precipitated by the addition at 0° C. of 1N hydrochloric acid. After drying under vacuum 0.42 g of the title compound was obtained as a solid. MS, m/z: 232 (M)+.

1. customAfter 14 hours the solvent was removed in vacuo
2. customthe title compound precipitated by the addition at 0° C. of 1N hydrochloric acid
3. dry with materialAfter drying under vacuum 0.42 g of the title compound
4. customwas obtained as a solid