Triethylamine hydrochloride → HCID 178515925, compound

HRID 1637357Notes

Reaction equation

HRID 1637357 reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([OH:9])=[CH:5][CH:4]=1)#[N:2].[N-:10]=[N+:11]=[N-:12].[Na+].Cl.C(N(CC)CC)C>C1(C)C=CC=CC=1>[OH:9][C:6]1[CH:7]=[CH:8][C:3]([C:1]2[NH:12][N:11]=[N:10][N:2]=2)=[CH:4][CH:5]=1

Participants

5

Reactant 3

HCID 11130Triethylamine hydrochlorideHCID 130194-CyanophenolHCID 33557Sodium Azide

Product 1

HCID 178515925HCID 178515925, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

Into the same device as used in Example 1 were placed 1.19 g (0.010 mole) of paracyanophenol, 1.95 g (0.030 mole) of sodium azide, 4.13 g (0.030 mole) of triethylamine hydrochloride and 12 ml of toluene. The mixture was reacted for 8 hours in the same manner as in Example 1, giving 1.34 g (0.0083 mole) of 5-(4-hydroxyphenyl)-1H-tetrazole (yield 82.7% based on paracyanophenol).

Workup

  1. customThe mixture was reacted for 8 hours in the same manner as in Example 1

Sources & evidence

ORD record
ord-f82a0ae4786c45b086c6e210f65f90bd
Source dataset
uspto-grants-2000_03
Patent number
US06040454

Reaction notes

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