Nitrogen → HCID 19839382, compound

HRID 1638906Notes

Reaction equation

HRID 1638906 reaction equation
Cl[C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([S:13](=[O:18])(=[O:17])[N:14]([CH3:16])[CH3:15])[N:8]=2)[N:5]=[CH:4][C:3]=1[C:19]([O:21][CH2:22][CH3:23])=[O:20].C(S)C1C=CC=CC=1.C(=O)([O-])[O-].[K+].[K+].N#N>CN(C)C=O>[CH3:15][N:14]([CH3:16])[S:13]([C:9]1[N:8]=[C:7]([N:6]2[C:2]([S:13]([NH2:14])(=[O:18])=[O:17])=[C:3]([C:19]([O:21][CH2:22][CH3:23])=[O:20])[CH:4]=[N:5]2)[CH:12]=[CH:11][CH:10]=1)(=[O:18])=[O:17]

Participants

6

Reactant 4

HCID 947NitrogenHCID 7509Benzyl mercaptanHCID 11430Potassium CarbonateHCID 19839416HCID 19839416, compound

Product 1

HCID 19839382HCID 19839382, compoundYield 186.3%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

To 50 ml of dried dimethylformamide, added were 4.2 g of ethyl 5-chloro-1-(6-dimethylsulfamoylpyridin-2-yl)pyrazole-4-carboxylate and 1.46 g of benzylmercaptan and 3.2 g of potassium carbonate, followed by stirring at room temperature for 24 hours in the atmosphere of N2. After the reaction, inorganic salt was filtered off and dimethylformamide was evaporated from the filtrate to obtain 4.4 g of the title compound as an oily product.

Workup

  1. customAfter the reaction, inorganic salt
  2. filtrationwas filtered off
  3. customdimethylformamide was evaporated from the filtrate

Sources & evidence

ORD record
ord-0ba6bb52e19b4f85991697019d548ad7
Source dataset
uspto-grants-1989_11
Patent number
US04881965

Reaction notes

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