Hydrogen Peroxide → Picolinic acid

HRID 1641672Notes

Reaction equation

HRID 1641672 reaction equation
[OH:1]O.[N:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[CH:9]=[O:10]>C(O)=O>[N:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[C:9]([OH:1])=[O:10]

Participants

4

Reactant 2

HCID 784Hydrogen PeroxideHCID 142732-Pyridinecarboxaldehyde

Product 1

HCID 1018Picolinic acid

Reagents, catalysts & solvents 1

HCID 284Formic AcidSolvent

Procedure

To mention specific examples of the reaction conditions, one to two equivalent amount of hydrogen peroxide is added to the pyridine-2-carbaldehyde derivative (8) in a formic acid solvent, and the mixture can be treated at room temperature for about 1 hour to 2 days, thus to produce the pyridine-2-carboxylic acid derivative (9).

Workup

  1. additionthe mixture can be treated at room temperature for about 1 hour to 2 days

Sources & evidence

ORD record
ord-832de3750c3c413e8112004fb4e6201b
Source dataset
uspto-grants-2012_02
Patent number
US08114886B2

Reaction notes

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