Ammonium → 2-Butyl-5-cyano-4-(1-hydroxy-1-methylpropyl)-1-tritylimidazole

HRID 164497Notes

Reaction equation

HRID 164497 reaction equation
[Br-:1].[CH2:4]([CH2:5][CH2:6][CH3:7])[c:8]1[n:9]([C:19]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:10]([C:17]#[N:18])[c:11]([C:13]([CH2:14][CH3:15])=[O:16])[n:12]1.[CH3:2][Mg+:3].[CH3:40][CH2:41][O:42][C:43](=[O:44])[CH3:45].[Cl-:38].[NH4+:39].[O:46]1[CH2:47][CH2:48][CH2:49][CH2:50]1>>[CH2:4]([CH2:5][CH2:6][CH3:7])[c:8]1[n:9]([C:19]([c:20]2[cH:21][cH:22][cH:23][cH:24][cH:25]2)([c:26]2[cH:27][cH:28][cH:29][cH:30][cH:31]2)[c:32]2[cH:33][cH:34][cH:35][cH:36][cH:37]2)[c:10]([C:17]#[N:18])[c:11]([C:13]([CH2:14][CH3:15])([OH:16])[CH3:40])[n:12]1

Participants

8

Reactant 7

HCID 223AmmoniumHCID 259Bromide ionHCID 312ChlorideHCID 8028TetrahydrofuranHCID 8857Ethyl AcetateHCID 190361902-Butyl-5-cyano-4-propionyl-1-tritylimidazoleHCID 178477777HCID 178477777, compound

Product 1

HCID 190361972-Butyl-5-cyano-4-(1-hydroxy-1-methylpropyl)-1-tritylimidazole

Sources & evidence

ORD record
ord-20d39d2c8aa049d7b5ada51066c4e444
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

Loading…