Dimethylformamide → 2,6-dichloro-N-[2-[(2-chlorocyclopropanecarbonyl)amino]-4-pyridinyl]benzamide

HRID 164719Notes

Reaction equation

HRID 164719 reaction equation
[CH3:64][CH2:65][O:66][C:67]([CH3:68])=[O:69].[CH:50]([N:51]([CH2:52][CH3:53])[CH:54]([CH3:55])[CH3:56])([CH3:57])[CH3:58].[Cl:19][CH:20]1[CH:21]([C:23](=[O:24])[OH:25])[CH2:22]1.[NH2:1][c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][C:9]([c:10]2[c:11]([Cl:17])[cH:12][cH:13][cH:14][c:15]2[Cl:16])=[O:18])[cH:7]1.[O:59]=[CH:60][N:61]([CH3:62])[CH3:63].[P-:26]([F:27])([F:28])([F:29])([F:30])([F:31])[F:32].[n:33]1([O:34][C:35]([N:36]([CH3:37])[CH3:38])=[N+:39]([CH3:40])[CH3:41])[c:42]2[n:43][cH:44][cH:45][cH:46][c:47]2[n:48][n:49]1>>[NH:1]([c:2]1[n:3][cH:4][cH:5][c:6]([NH:8][C:9]([c:10]2[c:11]([Cl:17])[cH:12][cH:13][cH:14][c:15]2[Cl:16])=[O:18])[cH:7]1)[C:23]([CH:21]1[CH:20]([Cl:19])[CH2:22]1)=[O:24]

Participants

8

Reactant 7

HCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 81531DiisopropylethylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 133995232-Chlorocyclopropane-1-carboxylic acidHCID 59618313N-(2-aminopyridin-4-yl)-2,6-dichlorobenzamide

Product 1

HCID 723403322,6-dichloro-N-[2-[(2-chlorocyclopropanecarbonyl)amino]-4-pyridinyl]benzamide

Sources & evidence

ORD record
ord-71b35d83a1854ea4a7c3b5caf7089ae3
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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