反应详情

2 g of 1-[3-(4- acetamido-2- methoxyphenoxy)-n-propyl]-4-phenyl-piperazine, 232 mg of 65% sodium hydride, 940 mg of 3-methyl-2- butenyl bromide and 60 ml of anhydrous dimethylformamide are treated in the same manner as described in Example 13. 1.78 g of 1-{3-[4-(N-acetyl-N-(3-methyl-2-butenyl)-amino)-2-methoxyphenoxy]-n-propyl}-4-phenyl-piperazine are thereby obtained as a pale yellow oil. Yield: 86.3%