Pyridine → N-{4-[(3-bromophenyl)amino]quinazolin-6-yl}-4-(4-ethylpiperazin-1-yl)but-2-ynamide
Reaction equation
[Br:30][c:31]1[cH:32][c:33]([NH:37][c:38]2[n:39][cH:40][n:41][c:42]3[cH:43][cH:44][c:45]([NH2:48])[cH:46][c:47]23)[cH:34][cH:35][cH:36]1.[CH2:16]([CH3:17])[N:18]1[CH2:19][CH2:20][N:21]([CH2:24][C:25]#[C:26][C:27](=[O:28])[OH:29])[CH2:22][CH2:23]1.[CH3:9][N:10]1[CH2:11][CH2:12][O:13][CH2:14][CH2:15]1.[Cl:1][C:2]([O:3][CH2:4][CH:5]([CH3:6])[CH3:7])=[O:8].[O:49]1[CH2:50][CH2:51][CH2:52][CH2:53]1.[cH:54]1[cH:55][cH:56][n:57][cH:58][cH:59]1>>[CH2:16]([CH3:17])[N:18]1[CH2:19][CH2:20][N:21]([CH2:24][C:25]#[C:26][C:27](=[O:29])[NH:48][c:45]2[cH:44][cH:43][c:42]3[n:41][cH:40][n:39][c:38]([NH:37][c:33]4[cH:32][c:31]([Br:30])[cH:36][cH:35][cH:34]4)[c:47]3[cH:46]2)[CH2:22][CH2:23]1Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-b07cfcbc5e984c9c912bc5fc9bb9e92a
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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