Diethyl ethylmalonate → HCID 19792074, compound

HRID 1655584Notes

Reaction equation

HRID 1655584 reaction equation
[CH2:1]([CH:3]([C:9]([O:11][CH2:12][CH3:13])=[O:10])[C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH3:2].C[Si]([N-][Si](C)(C)C)(C)C.[Na+].Cl[C:25]1[C:30]([N+:31]([O-:33])=[O:32])=[CH:29][CH:28]=[CH:27][N:26]=1>O1CCCC1>[N+:31]([C:30]1[C:25]([C:3]([C:9]([O:11][CH2:12][CH3:13])=[O:10])([C:4]([O:6][CH2:7][CH3:8])=[O:5])[CH2:1][CH3:2])=[N:26][CH:27]=[CH:28][CH:29]=1)([O-:33])=[O:32]

Participants

5

Reactant 3

HCID 8610Diethyl ethylmalonateHCID 796132-Chloro-3-nitropyridineHCID 2724254Sodium bis(trimethylsilyl)amide

Product 1

HCID 19792074HCID 19792074, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

Diethyl ethylmalonate is dissolved in tetrahydrofuran and treated with one equivalent of sodium bis(trimethylsilyl)amide followed by 2-chloro-3-nitropyridine to give the title compound.

Sources & evidence

ORD record
ord-0a4ce5da5d764fcdb3a463016abf605d
Source dataset
uspto-grants-1993_10
Patent number
US05250548

Reaction notes

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