Octanal → HCID 11063309, 화합물

HRID 1655658노트

반응식

HRID 1655658 반응식
[CH:1](=O)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8].[C:10]1(=[O:15])[CH2:14][CH2:13][CH2:12][CH2:11]1.[OH-].[Na+]>>[CH:1](=[C:11]1/[C:10](=[O:15])[CH2:14][CH2:13][CH2:12]/1)\[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH3:8]

참가 물질

4

반응물 3

HCID 454OctanalHCID 8452CyclopentanoneHCID 14798Sodium Hydroxide

생성물 1

HCID 11063309HCID 11063309, 화합물

실험 절차

The procedure was similar to that in Example 1 by reacting n-octanal with cyclopentanone in the presence of 1% NaOH to give 2-(E)-octylidene cyclopentanone. The boiling point of this intermediate compound was determined to be 120°-125° C. at a pressure of 4 mm Hg. A subsequent Mannich reaction yielded the 2-Dimethylaminomethyl-5-(E)-octylidene cyclopentanone hydrochloride. The melting point of the product was determined to be 138°-140° C.

출처 및 근거

ORD 기록
ord-3fea03f0848249f19f4b798fdeb15c6d
출처 데이터셋
uspto-grants-1993_10
특허 번호
US05250735

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