Water → HCID 15676484, compound

HRID 1656673Notes

Reaction equation

HRID 1656673 reaction equation
Br[CH2:2][C:3]1[C:8]2[N:9]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[S:11][C:7]=2[CH:6]=[CH:5][CH:4]=1.[C:18]([O-:21])(=[O:20])[CH3:19].[K+].O>CN(C)C=O>[C:18]([O:21][CH2:2][C:3]1[C:8]2[N:9]=[C:10]([C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)[S:11][C:7]=2[CH:6]=[CH:5][CH:4]=1)(=[O:20])[CH3:19]

Participants

5

Reactant 3

HCID 962WaterHCID 517044Potassium AcetateHCID 156764834-Bromomethyl-2-phenyl-benzothiazole

Product 1

HCID 15676484HCID 15676484, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

53 g (0.176 mol) of the compound from Example I and 20 g (0.2 mol) of potassium acetate were stirred at room temperature in 500 ml of dimethylformamide for 24 h, the solvent was stripped off in vacuo, water was added, and the product was filtered off with suction and dried. Yield: 46 g (92% of theory) M.p. 83°-84° C.

Workup

  1. additionwas added
  2. filtrationthe product was filtered off with suction
  3. customdried

Sources & evidence

ORD record
ord-bb6fb434361044ecbdec535f4dd75711
Source dataset
uspto-grants-1993_10
Patent number
US05254692

Reaction notes

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