Tetrahydrofuran → HCID 67337213, compound

HRID 1673048Notes

Reaction equation

[C:1]([N:8]1C=CN=C1)([N:3]1[CH:7]=[CH:6][N:5]=[CH:4]1)=[O:2].C([N:15]([CH2:18]C)CC)C.C1C[O:23]CC1>>[O:23]1[CH:18]=[N:15][NH:8][C:1]1=[O:2].[NH:3]1[CH:7]=[CH:6][N:5]=[CH:4]1

Participants

Reactant 3

HCID 8028Tetrahydrofuran

HCID 8471Triethylamine

HCID 682631,1'-Carbonyldiimidazole

Product 1

HCID 67337213HCID 67337213, compound

Procedure

As depicted in Scheme 41, the 1,3,4-oxadiazol-2(3H)-one-imidazole was synthesized by treatment of the hydrazide with carbonyldiimidazole and triethyl amine in THF.

Sources & evidence

ORD record: ord-4552f2f4196f412b8c90a6bacbdbd21f
Source dataset: uspto-grants-2011_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07998995B2

Reaction notes

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