Hydrochloric Acid → Methyl 6-(3-amino-1-pyrrolidinyl)-2-(2,4-difluorophenylamino)-5-fluoronicotinate
Reaction equation
[CH3:30][CH2:31][N:32]([CH2:33][CH3:34])[CH2:35][CH3:36].[CH3:37][CH2:38][O:39][CH2:40][CH3:41].[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[Cl:1][c:2]1[n:3][c:4]([NH:13][c:14]2[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]2)[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][c:11]1[F:12].[ClH:22].[ClH:23].[NH2:24][CH:25]1[CH2:26][NH:27][CH2:28][CH2:29]1>>[c:2]1([N:27]2[CH2:26][CH:25]([NH2:24])[CH2:29][CH2:28]2)[n:3][c:4]([NH:13][c:14]2[c:15]([F:21])[cH:16][c:17]([F:20])[cH:18][cH:19]2)[c:5]([C:6](=[O:7])[O:8][CH3:9])[cH:10][c:11]1[F:12]Participants
7
Reactant 6
Product 1
Sources & evidence
- ORD record
- ord-fe2618a8ea704093a31c819f49eed3ae
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…