Ammonium → N-[5-chloro-7-(3-methoxyprop-1-yn-1-yl)-1,3-benzodioxol-4-yl]-6-methoxy-7-(2-morpholin-4-ylethoxy)quinazolin-4-amine
Reaction equation
[CH3:16][O:17][c:18]1[cH:19][c:20]2[c:21]([O:37][c:38]3[c:39]([F:40])[c:41]([F:42])[c:43]([F:44])[c:45]([F:46])[c:47]3[F:48])[n:22][cH:23][n:24][c:25]2[cH:26][c:27]1[O:28][CH2:29][CH2:30][N:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1.[CH3:1][Si:2]([N-:3][Si:4]([CH3:5])([CH3:6])[CH3:7])([CH3:8])[CH3:9].[CH3:67][N:68]([CH3:69])[CH:70]=[O:71].[Cl-:65].[Cl:49][c:50]1[c:51]([NH2:64])[c:52]2[c:53]([c:57]([C:59]#[C:60][CH2:61][O:62][CH3:63])[cH:58]1)[O:54][CH2:55][O:56]2.[NH4+:66].[Na+:10].[O:11]1[CH2:12][CH2:13][CH2:14][CH2:15]1>>[CH3:16][O:17][c:18]1[cH:19][c:20]2[c:21]([NH:64][c:51]3[c:50]([Cl:49])[cH:58][c:57]([C:59]#[C:60][CH2:61][O:62][CH3:63])[c:53]4[c:52]3[O:56][CH2:55][O:54]4)[n:22][cH:23][n:24][c:25]2[cH:26][c:27]1[O:28][CH2:29][CH2:30][N:31]1[CH2:32][CH2:33][O:34][CH2:35][CH2:36]1Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-6129c33b3c154a3d811236c3766bb967
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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