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HRID1677372

反应详情

EQUATION

反应方程式

HRID 1677372 的结构方程式

REACTANTS

反应物

2
结构：CC(O)CN
HCID4

1-Amino-2-propanol

C3H9NO

结构：COc1cc(-c2cnc3[nH]cc(C(=O)O)c3n2)cc(OC)c1OC
HCID59540796

未命名化合物

PRODUCTS

生成物

1
结构：COc1cc(-c2cnc3[nH]cc(C(=O)NCC(C)O)c3n2)cc(OC)c1OC
HCID44206947

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

2-(3,4,5-Trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid (2-hydroxy-propyl)-amide was prepared starting from 2-(3,4,5-trimethoxy-phenyl)-5H-pyrrolo[2,3-b]pyrazine-7-carboxylic acid and 1-amino-propan-2-ol following the general procedures described in these Examples but with DMF as solvent. MP 201.9-202.6° C., M+H 387.