反应详情

A mixture of 5′-amino-2′-methyl-biphenyl-4-carboxylic acid [4-(1,1-dioxo-1lambda*6*-thiomorpholin-4-ylmethyl)-phenyl]-amide (54 mg), butyric acid (11 mg), EDAC (24 mg), HOBT (16 mg) and N-methylmorpholine (24 mg) in dry DMF (1 ml) was stirred at 20 C for 18 h. The mixture was then diluted with water (6 ml) and the resulting colourless solid collected by filtration and dried (42 mg).

1. filtrationthe resulting colourless solid collected by filtration
2. customdried (42 mg)