Divinyl sulfone → HCID 43581170, compound

HRID 1678506Notes

Reaction equation

HRID 1678506 reaction equation
[NH2:1][CH2:2][CH2:3][C:4]1[CH:9]=[CH:8][C:7]([NH2:10])=[CH:6][CH:5]=1.[CH:11]([S:13]([CH:16]=[CH2:17])(=[O:15])=[O:14])=[CH2:12].C(N(CC)CC)C>CN1C(=O)CCC1>[O:14]=[S:13]1(=[O:15])[CH2:16][CH2:17][N:1]([CH2:2][CH2:3][C:4]2[CH:9]=[CH:8][C:7]([NH2:10])=[CH:6][CH:5]=2)[CH2:12][CH2:11]1

Participants

5

Reactant 3

HCID 6496Divinyl sulfoneHCID 8471TriethylamineHCID 728952-(4-Aminophenyl)ethylamine

Product 1

HCID 43581170HCID 43581170, compound

Reagents, catalysts & solvents 1

HCID 13387N-methyl-2-pyrrolidoneSolvent

Procedure

A mixture of 4-(2-amino-ethyl)-phenylamine (1 g) and ethenesulfonyl-ethene (0.74 ml) in NMP (2.5 ml) containing triethylamine (1.02 ml) was heated to 110 C for 30 mins. The mixture was then allowed to cool and the solid produced was collected by filtration, washed with ether, and dried, giving the title compound as a pale yellow solid (1.59 g).

Workup

  1. temperaturewas heated to 110 C for 30 mins
  2. temperatureto cool
  3. customthe solid produced
  4. filtrationwas collected by filtration
  5. washwashed with ether
  6. customdried

Sources & evidence

ORD record
ord-3423c9b32d534ddaa779d6c9ae512534
Source dataset
uspto-grants-2011_08
Patent number
US08008303B2

Reaction notes

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