反应详情

A mixture of 3-allyl-4-hydroxy-5-methoxybenzaldehyde (10.25 g, 0.053 moles), dimethylformamide (150 ml), potassium carbonate (8.29 g, 0.06 moles) and 1-bromobutane (8.22 g, 0.06 moles) is kept at 40°-45° C. for 3 hours. The reaction mixture is dropped into iced water and the oil formed is extracted with dichloromethane. After washing with water, drying and evaporation of the solvent, a brown oil is obtained, which is passed through a bed of silica 60 to give a pale yellow oil of 3-allyl-4-butoxy-5-methoxybenzaldehyde (13 g, yield=91%).

1. customthe oil formed
2. extractionis extracted with dichloromethane
3. washAfter washing with water
4. customdrying
5. customevaporation of the solvent
6. customa brown oil is obtained