Hydrochloric Acid → 6-(4-Fluorophenyl)-N4-[3-fluoro-4-(1H-pyrrolo[2,3-b]pyridin-4-yloxy)phenyl]-pyrimidine-2,4-diamine
Reaction equation
[CH3:42][N:43]([CH3:44])[CH:45]=[O:46].[CH3:47][CH2:48][O:49][C:50](=[O:51])[CH3:52].[Cl:19][c:20]1[n:21][c:22]([NH2:33])[n:23][c:24](-[c:26]2[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]2)[cH:25]1.[ClH:34].[F:1][c:2]1[cH:3][c:4]([NH2:5])[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[nH:16][cH:17][cH:18]2.[Na+:35].[Na+:36].[O-:37][C:38](=[O:39])[O-:40].[OH2:41]>>[F:1][c:2]1[cH:3][c:4]([NH:5][c:20]2[n:21][c:22]([NH2:33])[n:23][c:24](-[c:26]3[cH:27][cH:28][c:29]([F:32])[cH:30][cH:31]3)[cH:25]2)[cH:6][cH:7][c:8]1[O:9][c:10]1[c:11]2[c:12]([n:13][cH:14][cH:15]1)[nH:16][cH:17][cH:18]2Participants
9
Reactant 8
Product 1
Sources & evidence
- ORD record
- ord-01b5e5924f80471e9e8a3535b0e1e79c
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
Loading…