Indole → HCID 11099672, compound
Reaction equation
Br[CH2:2][C:3]1[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[NH2:9][C:10]1[S:11][CH:12]=[CH:13][N:14]=1.N1C2C(=CC=CC=2)C=C1.[NH:24]1[C:32]2[C:27](=[CH:28][CH:29]=[CH:30][CH:31]=2)[C:26]([C:33]([O:35]C)=O)=[CH:25]1>>[S:11]1[CH:12]=[CH:13][N:14]=[C:10]1[NH:9][C:33]([C:26]1[C:27]2[C:32](=[CH:31][CH:30]=[CH:29][CH:28]=2)[N:24]([CH2:2][C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)[CH:25]=1)=[O:35]Participants
5
Procedure
R5Br=Bromomethylbenzene; NH2A=2-aminothiazole; Indole starting material=methyl indole 3-carboxylate
Sources & evidence
- ORD record
- ord-54e634340bab42fd81c503f70d09014b
- Source dataset
- uspto-grants-2012_04
- Patent number
- US08148413B2
Reaction notes
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