Methylamine → HCID 67264048, compound

HRID 1687584Notes

Reaction equation

HRID 1687584 reaction equation
[N+:1]([C:4]1[CH:15]=[CH:14][C:7]2[C:8](=[O:13])OC(=O)[NH:11][C:6]=2[CH:5]=1)([O-:3])=[O:2].[CH3:16][NH2:17]>C1COCC1>[NH2:11][C:6]1[CH:5]=[C:4]([N+:1]([O-:3])=[O:2])[CH:15]=[CH:14][C:7]=1[C:8]([NH:17][CH3:16])=[O:13]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 2820894-Nitro-isatoic anhydride

Product 1

HCID 67264048HCID 67264048, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent2×

Procedure

7-Nitro-1H-3,1-benzoxazine-2,4-dione (1.14 g, 0.00549 mol) was dissolved in THF (50 mL, 0.6 mol). 2 M of Methylamine in THF (10 mL) was added, and a yellow solid formed immediately. The reaction mixture was concentrated under reduced pressure to afford a light orange solid.

Workup

  1. customa yellow solid formed immediately
  2. concentrationThe reaction mixture was concentrated under reduced pressure
  3. customto afford a light orange solid

Sources & evidence

ORD record
ord-5490aeb9ffa549e19adc97176d7f67f3
Source dataset
uspto-grants-2012_04
Patent number
US08148391B2

Reaction notes

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