Methylamine → HCID 67274430, compound

HRID 1696781Notes

Reaction equation

HRID 1696781 reaction equation
C[O:2][C:3]([C:5]1[CH:10]=[C:9]([S:11][CH3:12])[CH:8]=[C:7]([NH2:13])[N:6]=1)=O.[CH3:14][NH2:15]>O1CCCC1>[CH3:14][NH:15][C:3]([C:5]1[CH:10]=[C:9]([S:11][CH3:12])[CH:8]=[C:7]([NH2:13])[N:6]=1)=[O:2]

Participants

4

Reactant 2

HCID 6329MethylamineHCID 67274196HCID 67274196, compound

Product 1

HCID 67274430HCID 67274430, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

A solution of 0.099 g 6-amino-4-methylsulfanyl-pyridine-2-carboxylic acid methyl ester in 2 ml methylamine 2M in tetrahydrofuran was kept at room temperature for 24 h. The solvents were evaporated and the residue was recrystallized from water to yield 0.054 g of the title compound as white crystals melting at 89-91° C.

Workup

  1. customThe solvents were evaporated
  2. customthe residue was recrystallized from water

Sources & evidence

ORD record
ord-cc98ba1b58a342768e820832139fa356
Source dataset
uspto-grants-2012_04
Patent number
US08163778B2

Reaction notes

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