Hydrochloric Acid → (3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidine-3-carboxylic acid methoxy-methyl-amide

HRID 169845Notes

Reaction equation

HRID 169845 reaction equation
[CH2:6]([c:7]1[cH:8][cH:9][cH:10][cH:11][cH:12]1)[N:13]1[CH2:14][CH:15]([C:26](=[O:27])[OH:28])[CH:16]([c:18]2[cH:19][c:20]([Cl:25])[c:21]([Cl:24])[cH:22][cH:23]2)[CH2:17]1.[CH3:2][NH:3][O:4][CH3:5].[CH3:58][CH2:59][O:60][C:61](=[O:62])[CH3:63].[ClH:1].[O:53]=[CH:54][N:55]([CH3:56])[CH3:57].[P-:29]([F:30])([F:31])([F:32])([F:33])([F:34])[F:35].[n:36]1([O:37][C:38]([N:39]([CH3:40])[CH3:41])=[N+:42]([CH3:43])[CH3:44])[c:45]2[n:46][cH:47][cH:48][cH:49][c:50]2[n:51][n:52]1>>[CH3:2][N:3]([O:4][CH3:5])[C:26]([CH:15]1[CH2:14][N:13]([CH2:6][c:7]2[cH:8][cH:9][cH:10][cH:11][cH:12]2)[CH2:17][CH:16]1[c:18]1[cH:19][c:20]([Cl:25])[c:21]([Cl:24])[cH:22][cH:23]1)=[O:27]

Participants

8

Reactant 7

HCID 313Hydrochloric AcidHCID 6228DimethylformamideHCID 8857Ethyl AcetateHCID 9886HexafluorophosphateHCID 14232N,O-DimethylhydroxylamineHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 16244042(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidine-3-carboxylic acid

Product 1

HCID 86627620(3RS,4SR)-1-Benzyl-4-(3,4-dichloro-phenyl)-pyrrolidine-3-carboxylic acid methoxy-methyl-amide

Sources & evidence

ORD record
ord-db8d35c53d0040afa0c855ed5dda5825
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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