Potassium Iodide → HCID 131723125, compound

HRID 1700949Notes

Reaction equation

HRID 1700949 reaction equation
[OH:1][C:2]1[CH:11]=[CH:10][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:4][CH:3]=1.[Si:12]([O:29][CH2:30][CH2:31]Br)([C:25]([CH3:28])([CH3:27])[CH3:26])([C:19]1[CH:24]=[CH:23][CH:22]=[CH:21][CH:20]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1.C(=O)([O-])[O-].[K+].[K+].[I-].[K+]>CC(C)=O>[Si:12]([O:29][CH2:30][CH2:31][O:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]([O:8][CH3:9])=[O:7])=[CH:10][CH:11]=1)([C:25]([CH3:26])([CH3:27])[CH3:28])([C:19]1[CH:20]=[CH:21][CH:22]=[CH:23][CH:24]=1)[C:13]1[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1

Participants

6

Reactant 4

HCID 4875Potassium IodideHCID 7456MethylparabenHCID 11430Potassium CarbonateHCID 10915442(2-Bromoethoxy)(tert-butyl)diphenylsilane

Product 1

HCID 131723125HCID 131723125, compound

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

A mixture of methyl 4-hydroxybenzoate (3.25 g, 22.0 mmol, 2-(tert-butyldiphenylsilyloxy) ethyl bromide (8.0 g, 22.0 mmol, powdered anhydrous potassium carbonate (12 g) and potassium iodide (0.1 g) in acetone (250 ml) was heated under reflux for 48 h. The solid was then filtered and the filtrate was evaporated under reduced pressure.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 48 h
  3. filtrationThe solid was then filtered
  4. customthe filtrate was evaporated under reduced pressure

Sources & evidence

ORD record
ord-fbe4bd08cf394f059711518b7bd8b379
Source dataset
uspto-grants-2002_02
Patent number
US06350892B1

Reaction notes

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