Dichloromethane → HCID 21527339, compound

HRID 1701228Notes

Reaction equation

HRID 1701228 reaction equation
[CH2:1]([O:3][C:4](=[O:19])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([S:14][CH3:15])[C:9]=1[C:16](=[O:18])[NH2:17])=[O:6])[CH3:2].ClC1C=C(C=CC=1)C(OO)=[O:25].C(Cl)Cl.C(=O)(O)[O-].[Na+]>O>[CH2:1]([O:3][C:4](=[O:19])[C:5]([NH:7][C:8]1[CH:13]=[CH:12][CH:11]=[C:10]([S:14]([CH3:15])=[O:25])[C:9]=1[C:16]([NH2:17])=[O:18])=[O:6])[CH3:2]

Participants

6

Reactant 4

HCID 6344DichloromethaneHCID 70297m-Chloroperbenzoic acidHCID 516892Sodium BicarbonateHCID 53960187HCID 53960187, compound

Product 1

HCID 21527339HCID 21527339, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

A mixture of 2.0 g. of [2-carbamyl-3-(methylthio)phenyl] oxamic acid ethyl ester and 1.44 g. of m-chloroperoxybenzoic acid in 200 ml. of methylene chloride is stirred for 2 hours. 0.6 g. of sodium bicarbonate in 20 ml. of water is added, the methylene chloride layer is separated, dried and evaporated. The residue is recrystallized from ethanol-diethyl ether, m.p. 164°-166° C.

Workup

  1. additionA mixture of 2.0 g
  2. customthe methylene chloride layer is separated
  3. customdried
  4. customevaporated
  5. customThe residue is recrystallized from ethanol-diethyl ether, m.p. 164°-166° C.

Sources & evidence

ORD record
ord-b9999489eaca44b69762bc70d2dfe458
Source dataset
uspto-grants-1980_03
Patent number
US04191840

Reaction notes

Loading…