Hydrochloric Acid → N-tert-Butyl-N'-[2,6-di(butan-2-yl)phenyl]thiourea

HRID 1701559Notes

Reaction equation

HRID 1701559 reaction equation
[CH:1]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([CH:11]([CH2:13][CH3:14])[CH3:12])[C:6]=1[N:15]=[C:16]=[S:17])([CH2:3][CH3:4])[CH3:2].Cl.[C:19]([NH2:23])([CH3:22])([CH3:21])[CH3:20]>>[CH:11]([C:7]1[CH:8]=[CH:9][CH:10]=[C:5]([CH:1]([CH2:3][CH3:4])[CH3:2])[C:6]=1[NH:15][C:16]([NH:23][C:19]([CH3:22])([CH3:21])[CH3:20])=[S:17])([CH2:13][CH3:14])[CH3:12]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 6385Tert-ButylamineHCID 20346983HCID 20346983, compound

Product 1

HCID 20347037N-tert-Butyl-N'-[2,6-di(butan-2-yl)phenyl]thiourea

Procedure

20.6 g of 2,6-di-sec.-butyl-phenyl isothiocyanate are dissolved in 20.0 g of tert.-butylamine and the batch is kept for 12 hours at 20° C. It is then poured into dilute hydrochloric acid and the reaction product is filtered off, washed until neutral and dried.

Workup

  1. filtrationthe reaction product is filtered off
  2. washwashed until neutral and
  3. customdried

Sources & evidence

ORD record
ord-18d5863ac5624e8da7056b87cf03180f
Source dataset
uspto-grants-1980_03
Patent number
US04194008

Reaction notes

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