Methyl iodide → HCID 20503815, compound

HRID 1702441Notes

Reaction equation

HRID 1702441 reaction equation
[CH2:1]([N:5]1[C:11](=[O:12])[C:10]2[N:13]([CH3:17])[N:14]=[C:15]([CH3:16])[C:9]=2[NH:8][C:7]2[N:18]=[CH:19][CH:20]=[CH:21][C:6]1=2)[CH2:2][CH2:3][CH3:4].[H-].[Na+].[CH3:24]I>CN(C)C=O>[CH2:1]([N:5]1[C:11](=[O:12])[C:10]2[N:13]([CH3:17])[N:14]=[C:15]([CH3:16])[C:9]=2[N:8]([CH3:24])[C:7]2[N:18]=[CH:19][CH:20]=[CH:21][C:6]1=2)[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 3

HCID 6328Methyl iodideHCID 24758Sodium hydrideHCID 20503814HCID 20503814, compound

Product 1

HCID 20503815HCID 20503815, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Prepared analogously to Example 6 from 9-(n-butyl)-1,3-dimethyl-1,4,9,10-tetrahydro-pyrazolo[4,3-e]pyrido[3,2-b][1,4]diazepin-10-one, sodium hydride, and methyl iodide in N,N-dimethylformamide with subsequent chromatographic purification.

Sources & evidence

ORD record
ord-0569121c30ea4feabec3621dbd521e19
Source dataset
uspto-grants-1983_04
Patent number
US04381303

Reaction notes

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