Sodium hydride → HCID 53986850, compound

HRID 1702890Notes

Reaction equation

HRID 1702890 reaction equation
[H-].[Na+].[CH2:3]([N:10]1[C:14]([C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)=[CH:13][NH:12][C:11]1=[O:21])[C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][CH:5]=1.[CH3:22][O:23][C:24](=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31]Br>CN(C=O)C>[CH3:22][O:23][C:24](=[O:33])[CH2:25][CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][N:12]1[CH:13]=[C:14]([C:15]2[CH:16]=[CH:17][CH:18]=[CH:19][CH:20]=2)[N:10]([CH2:3][C:4]2[CH:5]=[CH:6][CH:7]=[CH:8][CH:9]=2)[C:11]1=[O:21]

Participants

5

Reactant 3

HCID 24758Sodium hydrideHCID 10037742HCID 10037742, compoundHCID 11107373Methyl 8-bromooctanoate

Product 1

HCID 53986850HCID 53986850, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The product is produced as described in example 1 from 1.8 g of NaH (80% suspension in mineral oil), 15 g of 1-benzyl-5-phenyl-4-imidazolin-2-one, 120 cc. of DMF, 14.2 g of 8-bromocaprylic acid methyl ester and 1.8 g of NaJ.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-897b18ec15154767aa34fb6088d9f2f4
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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