Sodium hydride → HCID 54448380, compound

HRID 1702891Notes

Reaction equation

HRID 1702891 reaction equation
[H-].[Na+].[C:3]1([N:9]2[C:13]([C:14]3[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=3)=[C:12]([C:20]3[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=3)[NH:11][C:10]2=[O:26])[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH3:27][O:28][C:29](=[O:38])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36]Br>CN(C=O)C>[CH3:27][O:28][C:29](=[O:38])[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][CH2:36][N:11]1[C:12]([C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)=[C:13]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[N:9]([C:3]2[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=2)[C:10]1=[O:26]

Participants

5

Reactant 3

HCID 24758Sodium hydrideHCID 6285441,4,5-Triphenyl-1,3-dihydro-2H-imidazol-2-oneHCID 11107373Methyl 8-bromooctanoate

Product 1

HCID 54448380HCID 54448380, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The product is produced as described in example 1 from 1.2 g of NaH (80% suspension in mineral oil), 12 g of 1.4.5-triphenyl-4-imidazolin-2-one, 80 cc. of DMF, 9.5 g of 8-bromocaprylic acid methyl ester and 1.2 g of NaJ.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-bbc9fc1d55304cbb9162f34e39c4414c
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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