Sodium hydride → 11-(3-Ethyl-4.5-diphenyl-2-oxo-4-imidazolin-1-yl) undecanoic acid methyl ester

HRID 1702895Notes

Reaction equation

HRID 1702895 reaction equation
[H-].[Na+].[CH2:3]([N:5]1[C:9]([C:10]2[CH:15]=[CH:14][CH:13]=[CH:12][CH:11]=2)=[C:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[NH:7][C:6]1=[O:22])[CH3:4].[CH3:23][O:24][C:25](=[O:37])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35]Br>CN(C=O)C>[CH3:23][O:24][C:25](=[O:37])[CH2:26][CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][CH2:32][CH2:33][CH2:34][CH2:35][N:7]1[C:8]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)=[C:9]([C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][CH:15]=2)[N:5]([CH2:3][CH3:4])[C:6]1=[O:22]

Participants

5

Reactant 3

HCID 24758Sodium hydrideHCID 223913Methyl 11-bromoundecanoateHCID 126751261-ethyl-4,5-diphenyl-1,3-dihydro-2H-imidazol-2-one

Product 1

HCID 5392352611-(3-Ethyl-4.5-diphenyl-2-oxo-4-imidazolin-1-yl) undecanoic acid methyl ester

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

The product is produced as described in example 1 from 0.45 g of NaH (80% suspension in mineral oil), 4 g of 1-ethyl-4.5-diphenyl-4-imidazolin-2-one, 30 cc. of DMF, 4.2 g of 11-bromoundecanoic acid methyl ester and 0.45 g of NaJ.

Workup

  1. customThe product is produced

Sources & evidence

ORD record
ord-acbf12d29ed64f7e901fcc2f4c3f7fac
Source dataset
uspto-grants-1982_09
Patent number
US04349684

Reaction notes

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