(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochloride → D-Glucosamine

HRID 1708326Notes

Reaction equation

HRID 1708326 reaction equation
Cl.[OH:2][CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5].[Na]>CO>[OH:2][CH:3]1[O:11][C@H:10]([CH2:12][OH:13])[C@@H:8]([OH:9])[C@H:6]([OH:7])[C@H:4]1[NH2:5]

Participants

4

Reactant 2

HCID 2723635(3R,4R,5S,6R)-3-amino-6-(hydroxymethyl)oxane-2,4,5-triol hydrochlorideHCID 5360545Sodium

Product 1

HCID 439213D-Glucosamine

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

100 ml of methanol was put into a 200 ml conical flask, to which was added 6 g of D-glucosamine hydrochloride and 5 g of sodium metoxide, the mixture was stirred at a room temperature for one hour, and the resulting insoluble matter (sodium chloride) was filtered off to obtain a solution of free D-glucosamine.

Workup

  1. filtrationthe resulting insoluble matter (sodium chloride) was filtered off

Sources & evidence

ORD record
ord-3fc80c6500734c0abd16417ce35bf75d
Source dataset
uspto-grants-1994_10
Patent number
US05358538

Reaction notes

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