4-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid → Squalene

HRID 1708610Notes

Reaction equation

HRID 1708610 reaction equation
C1N(CCO)CCN([CH2:10][CH2:11]S(O)(=O)=O)C1.[F-].[K+].[CH2:18](S)[C@@H:19](O)[C@H:20](O)[CH2:21]S>>[CH3:18][C:19](=[CH:20][CH2:21][CH2:18]/[C:19](=[CH:20]/[CH2:21][CH2:10]/[C:11](=[CH:10]/[CH2:11][CH2:18]/[CH:19]=[C:20](/[CH2:21][CH2:18]/[CH:19]=[C:20](/[CH2:10][CH2:11][CH:10]=[C:10]([CH3:11])[CH3:11])\[CH3:21])\[CH3:21])/[CH3:20])/[CH3:19])[CH3:18]

Participants

4

Reactant 3

HCID 238314-(2-Hydroxyethyl)-1-piperazineethanesulfonic acid2×HCID 446094D-1,4-DithiothreitolHCID 522689Potassium Fluoride2×

Product 1

HCID 638072Squalene

Procedure

Buffer mixture contains 270 mM HEPES, pH 7.5, 20 mM Potassium fluoride and 5.4 mM Dithiothreitol(DTT). 55 μl of this mixture was used per assay. The final concentrations of HEPES, KF and DTT in the assay are 150 mM, 11 mM and 3 mM respectively.

Sources & evidence

ORD record
ord-cbdb6b1d40b34bcb829923a4c7d8d74f
Source dataset
uspto-grants-1994_10
Patent number
US05359096

Reaction notes

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