Ammonium → 4-chloro-3-(4-fluoro-phenyl)-5-tributylstannanyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrolo[2,3-b]pyridine

HRID 170994Notes

Reaction equation

HRID 170994 reaction equation
[Br:1][c:2]1[c:3]([Cl:26])[c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:18][O:19][CH2:20][CH2:21][Si:22]([CH3:23])([CH3:24])[CH3:25])[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1.[CH2:34]([CH2:35][CH2:36][CH3:37])[Sn:38]([CH2:39][CH2:40][CH2:41][CH3:42])([CH2:43][CH2:44][CH2:45][CH3:46])[Cl:47].[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:55][CH2:56][O:57][CH2:58][CH3:59].[CH:30]([Mg+:31])([CH3:32])[CH3:33].[Cl-:28].[Cl-:29].[Cl-:48].[Li+:27].[NH4+:49]>>[c:2]1([Sn:38]([CH2:34][CH2:35][CH2:36][CH3:37])([CH2:39][CH2:40][CH2:41][CH3:42])[CH2:43][CH2:44][CH2:45][CH3:46])[c:3]([Cl:26])[c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:18][O:19][CH2:20][CH2:21][Si:22]([CH3:23])([CH3:24])[CH3:25])[cH:9][c:10]2-[c:11]1[cH:12][cH:13][c:14]([F:17])[cH:15][cH:16]1

Participants

9

Reactant 8

HCID 223AmmoniumHCID 312Chloride3×HCID 3283Diethyl EtherHCID 8028TetrahydrofuranHCID 15096Tributyltin ChlorideHCID 28486Lithium ionHCID 575374765-bromo-4-chloro-3-(4-fluoro-phenyl)-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrolo[2,3-b]pyridineHCID 178461726HCID 178461726, compound

Product 1

HCID 575376414-chloro-3-(4-fluoro-phenyl)-5-tributylstannanyl-1-(2-trimethylsilanyl-ethoxymethyl)-1H-pyrrolo[2,3-b]pyridine

Sources & evidence

ORD record
ord-3fa38b92d29c447da510b670158df8b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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