Hydrochloric Acid → 2-Chloro-6-(4-ethanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

HRID 171657Notes

Reaction equation

HRID 171657 reaction equation
[CH2:32]([CH3:33])[S:34](=[O:35])(=[O:36])[Cl:37].[CH3:25][CH2:26][N:27]([CH2:28][CH3:29])[CH2:30][CH3:31].[Cl:1][c:2]1[n:3][c:4]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][NH:15][CH2:16][CH2:17]1)[s:10]2.[Cl:38][CH2:39][Cl:40].[ClH:24]>>[Cl:1][c:2]1[n:3][c:4]([N:18]2[CH2:19][CH2:20][O:21][CH2:22][CH2:23]2)[c:5]2[c:6]([n:7]1)[cH:8][c:9]([CH2:11][N:12]1[CH2:13][CH2:14][N:15]([S:34]([CH2:32][CH3:33])(=[O:35])=[O:36])[CH2:16][CH2:17]1)[s:10]2

Participants

6

Reactant 5

HCID 313Hydrochloric AcidHCID 6344DichloromethaneHCID 8471TriethylamineHCID 11667Ethanesulfonyl chlorideHCID 574940574-(2-Chloro-6-(piperazin-1-ylmethyl)thieno[3,2-d]pyrimidin-4-yl)morpholine

Product 1

HCID 866235402-Chloro-6-(4-ethanesulfonyl-piperazin-1-ylmethyl)-4-morpholin-4-yl-thieno[3,2-d]pyrimidine

Sources & evidence

ORD record
ord-eeb6e4cd47be488b8b70c93f41a9e102
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (9/10)

Reaction notes

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