Hydrochloric Acid → HCID 68510512, compound

HRID 1716869Notes

Reaction equation

HRID 1716869 reaction equation
C(OC(=O)[NH:7][CH:8]1[CH2:12][CH2:11][N:10]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[CH2:9]1)(C)(C)C.[ClH:19]>CO.C(O)(C)C>[Cl-:19].[Cl-:19].[NH2:7][CH:8]1[CH2:12][CH2:11][NH+:10]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[CH2:9]1.[NH2:7][CH:8]1[CH2:12][CH2:11][NH+:10]([CH:13]2[CH2:17][CH2:16][CH2:15][CH2:14]2)[CH2:9]1

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 68513412HCID 68513412, compound

Product 1

HCID 68510512HCID 68510512, compound

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 3776IsopropanolSolvent

Procedure

Pyrrolidin-3-yl-carbamic acid tert-butyl ester (9) (0.25 g, 1.00 mmol, 1 equiv) was dissolved in methanol (50 mL), followed by the addition of 5-6 N HCl in isopropanol (10 mL). The solution was stirred at room temperature for 24 h. The solution was evaporated under reduced pressure to give the title compound (0.22 g, 1.00 mmol, quantitative).

Workup

  1. customThe solution was evaporated under reduced pressure

Sources & evidence

ORD record
ord-55ff6e82c56847538653adf6232cd770
Source dataset
uspto-grants-2010_09
Patent number
US07803836B2

Reaction notes

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