反应详情

The compound, 5-benzyloxy-3-((E)-styryl)-1H-indazole is prepared according to procedure C, step Ib, using 300 mg of 5-benzyloxy-3-iodoindazole-1-carboxylic acid tert-butyl ester, 197 mg of E-phenylethenyl boronic acid, 192 mg of palladium tetrakistriphenylphosphine in suspension in 12 ml of dimethylformamide and 0.61 ml of a saturated sodium bicarbonate solution. The resulting crude product is treated as described hereinabove to obtain 150 mg of 5-benzyloxy-3-((E)-styryl)-1H-indazole.

1. customThe compound, 5-benzyloxy-3-((E)-styryl)-1H-indazole is prepared