Methane → 5-Ethoxypyrimidine

HRID 1728268Notes

Reaction equation

HRID 1728268 reaction equation
C(OC(C)C=CC1C=CC([C:14]2[N:19]=[CH:18][C:17]([O:20][CH2:21][CH3:22])=[CH:16][N:15]=2)=CC=1)(=O)C.C>[Pd].O1CCCC1>[CH2:21]([O:20][C:17]1[CH:16]=[N:15][CH:14]=[N:19][CH:18]=1)[CH3:22]

Participants

5

Reactant 2

HCID 297MethaneHCID 538992342-[4-(3-Acetoxy-1-butenyl)phenyl]-5-ethoxypyrimidine

Product 1

HCID 199216885-Ethoxypyrimidine

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 8028TetrahydrofuranSolvent

Procedure

9 g of 2-[4-(3-acetoxy-1-butenyl)phenyl]-5-ethoxypyrimidine, 2 g of palladium on active charcoal (10 wt. %) and 150 ml of tetrahydrofuran were hydrogenated in an analogous manner to Example 1(e) to give 8.2 g of 2-(3-acetoxy-1-butyl)phenyl]-5-(ethoxy)pyrimidine.

Sources & evidence

ORD record
ord-722e6aca303a45a698cae6c0b9f8ad49
Source dataset
uspto-grants-1994_07
Patent number
US05326497

Reaction notes

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