Triphenylphosphine → HCID 67635417, compound

HRID 1728279Notes

Reaction equation

HRID 1728279 reaction equation
[CH2:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([OH:22])=[CH:18][N:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH3:3].[CH2:23](O)[CH2:24]/[CH:25]=[CH:26]\[CH2:27][CH2:28][CH2:29][CH3:30].N(C(OCC)=O)=NC(OCC)=O.C1(P(C2C=CC=CC=2)C2C=CC=CC=2)C=CC=CC=1>O1CCCC1>[CH2:1]([O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][C:10]1[CH:15]=[CH:14][C:13]([C:16]2[CH:21]=[CH:20][C:19]([O:22][CH2:23][CH2:24]/[CH:25]=[CH:26]\[CH2:27][CH2:28][CH2:29][CH3:30])=[CH:18][N:17]=2)=[CH:12][CH:11]=1)[CH2:2][CH3:3]

Participants

6

Reactant 4

HCID 11776TriphenylphosphineHCID 220568ethyl N-ethoxycarbonyliminocarbamateHCID 53645193-Octen-1-ol, (3Z)-HCID 190170922-[4-(5-[Propyloxy]-1-pentyl)phenyl]-5-hydroxypyridine

Product 1

HCID 67635417HCID 67635417, compoundYield 59.6%

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Procedure

1.0 g of 2-[4-(5-[propyloxy]-1-pentyl)phenyl]-5-hydroxypyridine, 0.42 g of (Z)-3-octen-1-ol, 0.58 g of diethyl azodicarboxylate, 0.88 g of triphenylphosphine and 100 ml of tetrahydrofuran are reacted in an analogous manner to Example 3 to give 0.8 g of 2-[4-(5-[propyloxy]-1-pentyl)phenyl]-5-([(Z)-3-octenyl]oxy)pyridine.

Sources & evidence

ORD record
ord-5146ff67b9244daa917fa13402352325
Source dataset
uspto-grants-1994_07
Patent number
US05326497

Reaction notes

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