Hydrochloric Acid → tert-butyl 4-hydroxy-4-(1H-imidazol-2-yl)piperidine-1-carboxylate
Reaction equation
[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[CH2:6]([Li:7])[CH2:8][CH2:9][CH3:10].[CH3:31][CH2:32][O:33][C:34](=[O:35])[CH3:36].[ClH:25].[O:11]=[C:12]1[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]1.[nH:1]1[cH:2][n:3][cH:4][cH:5]1>>[nH:1]1[c:2]([C:12]2([OH:11])[CH2:13][CH2:14][N:15]([C:18](=[O:19])[O:20][C:21]([CH3:22])([CH3:23])[CH3:24])[CH2:16][CH2:17]2)[n:3][cH:4][cH:5]1Participants
7
Sources & evidence
- ORD record
- ord-d64c0eba2a5649239f84b84dc6991509
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (9/10)
Reaction notes
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